The Institute for Neurosciences of Montpellier (INM) is the Joint Research Unit U1298 Inserm/University of Montpellier. It comprises 8 Inserm teams and a staff of 200 personnel working on sensory-motor deficits and neurodegeneration. INM aims to gather fundamental and translational research to study the development, synaptic plasticity and integration, and neurodegenerative processes leading to disorders of the central and sensory-motor systems.
Our fundamental research is the ground for the development of innovative therapeutic (cell and gene therapy) and diagnostic (genetics and proteomics) strategies for hereditary retinal and optic nerve blindness, corneal damages, auditory neuropathy (deafness and tinnitus), somatosensory diseases (touch and pain), sleep disorders, cognition disorders (autism, schizophrenia, environmental stress) and neurodegenerative diseases (amyotrophic lateral sclerosis, multiple sclerosis, Alzheimer's disease).
Research, from the molecular level to the integrated system, is conducted using cutting-edge technical platforms (functional analysis, stem cell and organoids, neurogenetics, proteomics, biostatistics and epidemiology, photonic and electronic imaging). Our translational research is based on strong interactions with clinical services (neurology, ophthalmology, ENT). We benefit from the support of patient associations and interact constructively with industry.
Identification of a new gene causing both dominant and recessive forms of the most frequent blinding inherited disorder: retinitis pigmentosa
The mutated form of SOD1 causing Charcot's Disease differentially disrupts motor neurons ans muscle
A new component of the synapse, TMEM16F, involved in ALS
INM joins the CRISPR/Cas community
Mitochondrial DNA is implicated in a new surprising phenotype
Four INM teams participated in the Apprentice Researcher program, out of the 11 that were coordinated by Genopolys this year. The number of sessions had to be reduced this year (5 lab sessions for most of the students instead of 9), due to the containment caused by the Coronavirus. However, in order to close this experience in a constructive way, the coordinators, Magali Kitzmann and Marie Péquignot, proposed to the supervisors and the Apprentices to prepare a 10-minute presentation which was filmed, for the most part live, on Wednesday 10 June 2020. Discover the second Apprentice Researcher Congress in virtual format!