The genetic and clinical relevance of neuroinflammation in ALS.

Our vision is to direct a translational research integrating a clinical research, at the ALS center of Gui-de-Chauliac and genetic insights, at the genetic department of the Nîmes hospital.

Motoneuron 4

 

Clinical prospective studies with molecular diagnosis, association studies of single nucleotide polymorphisms as well as the forthcoming introduction of Next Generation Sequencing to conduct large-scale genetic studies provide us the means to evaluate the human relevance of our fundamental research.

 

 

 

 

External link: La Clinique du Motoneurone

http://www.cliniquedumotoneurone.fr

 

Major publications

Mouzat, K et al., Int J Mol Sci. 20, 1-17. 2019
Nicolas, A et al., Neuron, 97, 1268-1283, 2018
Mouzat K., et al., Mol Neurobiol. 55(3):1959-1965, 2018
Mouzat K., et al., Cell Mol Life Sci. 73(20):3801-8, 2016
Camu W., et al., Neurobiol Aging. 35(5):1198-205, 2014
Masseret E., et al., PLOS One. 8(12):e83406, 2013
Benajiba L., et al. Ann Neurol. 65(4):470-3, 2009
Kabashi E., et al., Nat Genet. 40(5):572-4, 2008

 

 

Collaborations

  • Guy Rouleau (MNI, Montreal, Canada)
  • Paul Cox (Institute for Ethnomedicine, Jackson, USA)
  • Estelle Masseret (UMR5119, Montpellier, France)
  • Pierre-Marie Preux (UMR1094, Limoges, France)
  • Edor Kabashi (ICM, Paris, France)

 

Fundings

CHU MontpellierCHU NimesNimes Métropole

 

Contact

Camu William

Lumbroso Serge