The genetic and clinical relevance of neuroinflammation in ALS.

Our vision is to direct a translational research integrating a clinical research, at the ALS center of Gui-de-Chauliac and genetic insights, at the genetic department of the Nîmes hospital.

Motoneuron 4

 

Clinical prospective studies with molecular diagnosis, association studies of single nucleotide polymorphisms as well as the forthcoming introduction of Next Generation Sequencing to conduct large-scale genetic studies provide us the means to evaluate the human relevance of our fundamental research.

 

 

 

 

External link: La Clinique du Motoneurone

http://www.cliniquedumotoneurone.fr

 

Major publications

Mouzat K., et al., Mol Neurobiol. 2017

Mouzat K., et al., Cell Mol Life Sci. 2016

Camu W., et al., Neurobiol Aging. 2014

Masseret E., et al., PLOS One. 2013

Benajiba L., et al. Ann Neurol. 2009

Mouzat K., et al., Endocrinology. 2009

Kabashi E., et al., Nat Genet. 2008

 

Collaborations

  • Guy Rouleau (MNI, Montreal, Canada)
  • Paul Cox (Institute for Ethnomedicine, Jackson, USA)
  • Estelle Masseret (UMR5119, Montpellier, France)
  • Pierre-Marie Preux (UMR1094, Limoges, France)
  • Edor Kabashi (ICM, Paris, France)

Contact

Camu William

Lumbroso Serge